Supplements for PCOS (And Why Everyone’s Supplement Stack Looks Different)

If you caught my latest Reel, you saw me unbox my most recent Fullscript order — aka, the exact supplements I’m taking right now to manage my PCOS naturally.
But before I get into my personal stack, let’s zoom out.
Whether you’re newly diagnosed or just trying to get your symptoms under control, you’ve probably already Googled “best supplements for PCOS” and found a million suggestions.
Not all of them are necessary — and some might even backfire if they’re not right for your root causes.
But there are a few that I do recommend to almost everyone with PCOS, even before we even dive into advanced testing.
Top 5 Supplements for PCOS (That Almost Everyone Can Benefit From)
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Ovasitol (Myo- & D-Chiro Inositol Blend)
– The gold standard for PCOS. It improves insulin sensitivity, supports regular ovulation, reduces cravings, and may lower androgens.
– Best for: Irregular cycles, sugar cravings, fertility, insulin resistance, and mood swings. -
Magnesium Glycinate or Citrate
– Most women are deficient, and it’s essential for blood sugar balance, sleep, stress management, and reducing inflammation.
– Best for: Anxiety, fatigue, sleep issues, cravings, and hormone regulation. -
Berberine
– Comparable to metformin in research. Supports insulin sensitivity, blood sugar control, and appetite regulation.
– Best for: Belly fat, carb cravings, elevated glucose, and high androgens. -
Vitamin D3 + K2
– Vital for hormone production, mood, immune health, and fertility. Often deficient in women with PCOS.
– Best for: Low energy, irregular periods, PMS, and hormone regulation. -
DIM + I3C (Estrogen Detox Support)
– Supports liver detox pathways that metabolize excess estrogen — which is crucial if you're estrogen dominant (like me).
– Best for: Hormonal acne, PMS, bloating, breast tenderness, and cycle regulation.
⚠️ A Quick Note on Personalization
These supplements are a great starting point but they aren’t a blanket solution. Every woman’s PCOS is different. Some struggle with insulin resistance, others with inflammation or adrenal issues, and many deal with some combination of all three.
In my program, PCOS Made Manageable, I don’t hand out the same protocol to everyone. Each client gets personalized recommendations based on their symptoms, goals, and (if we’ve run labs) their hormone levels.
And you get 25% off your Fullscript orders as part of the program!
What I’m Taking Right Now for PCOS
Here’s what I’m currently using — my main focus is estrogen detox, progesterone support, and blood sugar balance for appetite and cravings:
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Collagen Protein
For gut healing, hormone production, skin, joints, and a blood sugar-stabilizing source of protein. -
Magnesium (Triple Complex)
For blood sugar regulation, sleep, cravings, and to calm my nervous system. -
Liposomal Vitamin C
Powerful antioxidant and supports proper estrogen metabolism and immune function. -
Berberine
My go-to for appetite control, blood sugar support, and post-meal glucose regulation. -
Ovasitol
A must-have for cravings, ovulation, and supporting insulin sensitivity. -
Vitamin D + K2
Helps balance hormones, support mood, and promote healthy cycles. -
L-Glutamine
Incredible for gut repair and calming sugar cravings (especially during PMS). -
Zinc
For skin, immune health, inflammation support, and ovulatory function. -
DIM + I3C
Crucial for estrogen clearance. I’m very estrogen dominant, and this helps me detox and balance out my cycle. -
GLP-1 Probiotic Pro
Supports satiety hormones, gut health, and appetite regulation. -
Progesterone Cream
Game-changer. Helps balance estrogen, improve sleep, reduce PMS symptoms, and support my overall hormonal rhythm.
Final Thoughts
Supplements aren’t a shortcut but they are a powerful tool when used the right way.
If you’re overwhelmed with figuring out which ones you actually need, that’s exactly what I help with inside PCOS Made Manageable. You’ll get a clear nutrition & training plan, customized supplement recommendations, 1:1 support, and a whole lot of clarity.
👉 Want help figuring out your root causes and building your supplement protocol? Apply for PCOS Made Manageable.
👉 Want to order some of my Fullscript favorites? Here’s the link.